Concern
By way of your last answer.
That is my 2nd time we delivered this concern.
I have re-done an intensive research about the structure of male genitalia. In a nutshell, as it happens that information out there was inconsistent. In Wikipedia, two split entries of Foreskin’ and Mucous membrane’ yield contradictory outcomes: the previous states the glans penis (head for the penis) and glans clitoridis plus the inside the prepuce (foreskin) and clitoral bonnet are perhaps not mucous membranes’, even though the latter says that the internal foreskin is a mucous membrane layer just like the inside the eyelid or the lips. ‘ in addition, relating to glans penis’ of wikipedia, The epithelium regarding the glans penis is mucocutaneous muscle.’
Because of the real way i discovered that the foreskin consists of Langerhans cells that are defined as receptor of HIV virus (these records arises from OU Handbook of GUM and HIV medicine).
I’ve talked about these problems having a psychiatrist (this is because i’m i am incredibly concerned throughout the whole HIV/STD thingy) who warned me that i willn’t be doing penis-to-penis side-along rubbing and penis docking more because `it’s rubbing of mucosal cells. HIV/STD virus is likely to pass between. Why can you just take such dangers?’
In your final answer (answer that is final), you stated that the transmission danger of dick-docking is basically nonexistent and implied that penis-to-penis rubbing that is side-along perhaps maybe not pose any transmission danger since the only mucous membrane regarding the entire cock (including shaft, foreskin, glans penis) may be the liner associated with urethra through the pee-hole up to your bladder. But i did not point out that i am uncircumcised. There is a great amount of internal foreskin whose really nature is very dubious of mucous membrane layer and that will be high in Langerhans cells.
So my questions are: (1) might you please reiterate your opinion from the transmission danger of dick-docking and penis-to-penis rubbing that is side-along citing the real reason for?? let’s say certainly one of us shot the strain? Would the strain shoot right at the urethra during docking. (2) should we put https://www.datingmentor.org/bumble-vs-okcupid/ on a condom although we do dick-docking and penis-to-penis side-along rubbing? (3) can I do a circumcision, as some studies from Kenya(!) suggest it decreases the possibility of transmission of HIV along with other STDs? Do it is believed by you?? (4) exactly why are Langerhans cells cited as vunerable to HIV infection? exactly just What role does it play ?? (5) how come the word `mucous membrane layer’ so essential in HIV illness? The facts anyhow?? Would HIV or any other STDs get throughout the membrane layer and infect other people??
As bothersome as i will be, we sincerely do hope that you wouldn’t find my queries unpleasant or devious at all. Debate contributes to better understanding. In an effort for me personally to possess some type of comfort, might you painstakingly respond to my concerns??
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Solution
My estimation HIV that is regarding transmission/acquisition to frottage (penis-to-penis rubbing, “dick-docking”) remains unchanged. It is really not regarded as a danger. Could you shoot lots and hit the urethra? Yes, it really is theoretically feasible, while not totally possible, that the spunk would in fact come right into significant experience of the urethra’s mucous membrane layer.
If that would make you’re feeling safer much less anxious, certain. Really, I do not feel it really is necessary.
The studies do indicate that male circumcision decreases the chance for acquiring HIV. Nevertheless, in the event that you follow safer intimate practices, I don’t feel it is necessary.
Langerhan’s cells (dendritic cells) perform a crucial role in the initiation of HIV illness by virtue associated with the cap cap ability of HIV to bind to certain cell area receptors of those cells. This permits efficient presentation of HIV to CD4 cells that then become infected. The foreskin contains Langerhan’s cells.
A membrane that is mucous a slim layer (membrane layer) that lines all interior human anatomy passages that communicate straight with atmosphere outside of the human body, like the breathing and alimentary tracts, and that has specialized cells or glands that secrete mucous. HIV can permeate mucous membranes, however it cannot permeate skin that is intact. The foreskin just isn’t a mucous membrane layer. Nonetheless, it’s a specific types of epidermis and HIV could be adopted because of the Langerhan’s (dendritic) cells positioned inside the foreskin.
We certainly do not find your inquiries either devious or”offensive.” It may be somewhat confusing to try and explain complex information on physiology or the purpose of specific cells in a forum similar to this forum. Therefore the physiology concept has ended for today.